Recombinant Human MYO1G Protein (Gly769-Pro1016), His tagged

• Cat.No.: MYO1G-3641H
• Product Overview: Recombinant human MYO1G (Gly769-Pro1016) protein fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Gly769-Pro1016
• Description: Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.
• Molecular Mass: 29.59 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: MYO1G myosin IG [ Homo sapiens (human) ]
• Official Symbol: MYO1G
• Synonyms: HA2; MHAG
• Gene ID: 64005
• mRNA Refseq: NM_033054
• Protein Refseq: NP_149043
• MIM: 613445
• UniProt ID: B0I1T2