Recombinant Human MTOR, MYC/DDK-tagged
Cat.No. : | MTOR-156H |
Product Overview : | Recombinant Human MTOR, fused with C-terminal MYC/DDK, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. |
Molecular Mass : | 288.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | MTOR mechanistic target of rapamycin (serine/threonine kinase) [ Homo sapiens (human) ] |
Official Symbol | MTOR |
Synonyms | MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; mechanistic target of rapamycin (serine/threonine kinase); serine/threonine-protein kinase mTOR; rapamycin target protein 1; mammalian target of rapamycin; rapamycin and FKBP12 target 1; FKBP-rapamycin associated protein; rapamycin associated protein FRAP2; FKBP12-rapamycin complex-associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; NP_004949.1; EC 2.7.1.1; EC 2.7.11.1 |
Gene ID | 2475 |
mRNA Refseq | NM_004958 |
Protein Refseq | NP_004949 |
MIM | 601231 |
UniProt ID | P42345 |
Chromosome Location | 1p36.2 |
Pathway | Acute myeloid leukemia; Alpha6-Beta4 Integrin Signaling Pathway; Class I PI3K signaling events mediated by Akt |
Function | ATP binding; RNA polymerase III type 1 promoter DNA binding; TFIIIC-class transcription factor binding |
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◆ Cell & Tissue Lysates | ||
MTOR-4068HCL | Recombinant Human MTOR 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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