Recombinant Human MSLN protein, His-tagged, Biotin Labeled.
| Cat.No. : | MSLN-10623H |
| Product Overview : | Recombinant Human MSLN(Glu 296 - Gly 580) fused with His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
| Description : | Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His |
| Predicted N Terminal : | Glu 296 |
| Form : | Lyophilized from 0.22µm filtered solution in PBS (pH 7.4) with Trehalose as protectant. |
| Molecular Mass : | The protein has a calculated MW of 33 kDa. The protein migrates as 38-42 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation. |
| Protein length : | Glu 296 - Gly 580 |
| Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
| Purity : | >95% as determined by SDS-PAGE. |
| Notes : | The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product. |
| Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
| Reconstitution : | Reconstitute at 100 μg/mL in sterile deionized water. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the COA. |
| Gene Name | MSLN mesothelin [ Homo sapiens ] |
| Official Symbol | MSLN |
| Synonyms | MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP; |
| Gene ID | 10232 |
| mRNA Refseq | NM_001177355 |
| Protein Refseq | NP_001170826 |
| MIM | 601051 |
| UniProt ID | Q13421 |
| Chromosome Location | 16p13.3 |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All MSLN Products
Required fields are marked with *
My Review for All MSLN Products
Required fields are marked with *
0
Inquiry Basket
