Recombinant Human MRPS15 Protein, His-tagged

• Cat.No.: MRPS15-1942H
• Product Overview: Recombinant human MRPS15 protein, fused to His-tagged at N-terminus, was expressed in E. coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. Store at -80 Centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 29.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MRPS15 mitochondrial ribosomal protein S15 [ Homo sapiens ]
• Official Symbol: MRPS15
• Synonyms: DC37; MPR-S15; RPMS15; S15mt
• Gene ID: 64960
• mRNA Refseq: NM_031280
• Protein Refseq: NP_112570
• MIM: 611979
• UniProt ID: P82914