MRPS15
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Official Full Name
mitochondrial ribosomal protein S15 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q. -
Synonyms
MRPS15;mitochondrial ribosomal protein S15;28S ribosomal protein S15, mitochondrial;FLJ11564;MRP-S15;DC37;S15mt;RPMS15;MPR-S15
Recombinant Proteins
- Human
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPS15-1021H | Recombinant Human MRPS15, GST-tagged | E.coli | Human | GST | 1-257aa | |
| MRPS15-1108H | Recombinant Human MRPS15 | Mammalian Cells | Human | His |
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| MRPS15-3778R | Recombinant Rat MRPS15 Protein | Mammalian Cells | Rat | His |
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| MRPS15-613Z | Recombinant Zebrafish MRPS15 | Mammalian Cells | Zebrafish | His |
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| MRPS15-4150HCL | Recombinant Human MRPS15 293 Cell Lysate | HEK293 | Human | Non |
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| MRPS15-1942H | Recombinant Human MRPS15 Protein, His-tagged | E.coli | Human | His |
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| MRPS15-3437R | Recombinant Rat MRPS15 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| MRPS15-3437R-B | Recombinant Rat MRPS15 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| MRPS15-3523H | Recombinant Human MRPS15 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| MRPS15-3523H-B | Recombinant Human MRPS15 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| MRPS15-5603H | Recombinant Human MRPS15 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MRPS15-6467HF | Recombinant Full Length Human MRPS15 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 257 amino acids |
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Involved Pathway
MRPS15 involved in several pathways and played different roles in them. We selected most pathways MRPS15 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL7A,RPL8,RPL37,RPS8B,RPS27,MRPL15,RPS13,RPL28,RPL9,RPL10L |
Protein Function
MRPS15 has several biochemical functions, for example, poly(A) RNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS15 itself. We selected most functions MRPS15 had, and list some proteins which have the same functions with MRPS15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | HIST1H1B,CDK5R2,CRKL,LUC7L3,NKAP,POLR2A,HLTF,RRP9,EIF1B,ZAK |
| structural constituent of ribosome | UBA52,RPL30,NDUFA7,MRPS21,RPL10,MRPL46,RPS9,RPL38,RPS26L,RPS27.1 |
Interacting Protein
MRPS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS15.
ESR2;PTCD3;Brwd3;ssrna_ug;ACSL4;ESR1;Nfyc;MPP1;HNRNPU;ORC1;ICT1;Prmt6;CDC73;Pcgf1;MRPS27;VPS16;AGO1;PHF8
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