Recombinant Human MRPL13, His-tagged

• Cat.No.: MRPL13-7574H
• Product Overview: Recombinant human MRPL13 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Antigen Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL13 is a 39S subunit protein.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
• Molecular Mass: 23.1 kDa (201aa)
• Protein length: 1-178aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSFSRA PQQWATFARI WYLLDGKMQP PGKLAAMASI RLQGLHKPVY HALSDCGDHV VIMNTRHIAF SGNKWEQKVY SSHTGYPGGF RQVTAAQLHL RDPVAIVKLA IYGMLPKNLH RRTMMERLHL FPDEYIPEDI LKNLVEELPQ PRKIPKRLDE YTQEEIDAFP RLWTPPEDYR L
• Purity: >85% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: MRPL13 mitochondrial ribosomal protein L13 [ Homo sapiens ]
• Official Symbol: MRPL13
• Synonyms: MRPL13; mitochondrial ribosomal protein L13; 39S ribosomal protein L13, mitochondrial; L13; L13A; L13mt; RPL13; RPML13; MRP-L13
• Gene ID: 28998
• mRNA Refseq: NM_014078
• Protein Refseq: NP_054797
• MIM: 610200
• UniProt ID: Q9BYD1
• Chromosome Location: 8q22.1-q22.3
• Pathway: Ribosome, organism-specific biosystem; Ribosome, conserved biosystem
• Function: protein binding; structural constituent of ribosome