Recombinant Human MRI1 Protein, MYC/DDK-tagged

• Cat.No.: MRI1-1551H
• Product Overview: Recombinant Human MRI1 Protein was expressed in human HEK293 cells with C-terminal MYC/DDK-tag.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).
• Form: Liquid
• Molecular Mass: 39 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: MRI1 methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: MRI1
• Synonyms: MRI1; methylthioribose-1-phosphate isomerase homolog (S. cerevisiae); methylthioribose-1-phosphate isomerase; MGC3207; MTNA; Ypr118w; M1Pi; MTR-1-P isomerase; mediator of RhoA-dependent invasion; S-methyl-5-thioribose-1-phosphate isomerase; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
• Gene ID: 84245
• mRNA Refseq: NM_001031727
• Protein Refseq: NP_001026897
• MIM: 615105
• UniProt ID: Q9BV20