Recombinant Human MREG, His-tagged

• Cat.No.: MREG-5086H
• Product Overview: Recombinant human MREG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Melanoregulin, also known as MREG, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG is expressed in photoreceptor cells as two isoforms due to alternative splicing. MREG interacts with Peripherin-2, a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 27.3 kDa (237aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGLRDWL RTVCCCCGCE CLEERALPEK EPLVSDNNPY SSFGATLVRD DEKNLWSMPH DVSHTEADDD RTLYNLIVIR NQQAKDSEEW QKLNYDIHTL RQVRREVRNR WKCILEDLGF QKEADSLLSV TKLSTISDSK NTRKAREMLL KLAEETNIFP TSWELSERYL FVVDRLIALD AAEEFFKLAR RTYPKKPGVP CLADGQKELH YLPFPSP
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by BCA assay)

Gene Information

• Gene Name: MREG melanoregulin [ Homo sapiens ]
• Official Symbol: MREG
• Synonyms: MREG; melanoregulin; DSU; FLJ10116; WDT2; whn-dependent transcript 2; dilute suppressor protein homolog; MGC90296
• Gene ID: 55686
• mRNA Refseq: NM_018000
• Protein Refseq: NP_060470
• MIM: 609207
• UniProt ID: Q8N565
• Chromosome Location: 2q35