Recombinant Human MMRN1 protein, His-tagged

• Cat.No.: MMRN1-7952H
• Product Overview: Recombinant Human MMRN1 aa. (Ala807~Gly1053 (Accession # Q13201)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Ala807~Gly1053
• Description: Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.6kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: MMRN1 multimerin 1 [ Homo sapiens (human) ]
• Official Symbol: MMRN1
• Synonyms: MMRN1; multimerin 1; ECM; MMRN; GPIa*; EMILIN4; multimerin-1; EMILIN-4; elastin microfibril interface located protein 4; elastin microfibril interfacer 4; endothelial cell multimerin; glycoprotein Ia*
• Gene ID: 22915
• mRNA Refseq: NM_007351.2
• Protein Refseq: NP_031377.2
• UniProt ID: Q13201