Recombinant Human MMP9, His-tagged

• Cat.No.: MMP9-44H
• Product Overview: Recombinant Human Neutrophil Gelatinase Associated Lipocalin is expressed inE. colihaving a molecular weight of 28.1 kDa fused to an amino terminal hexahistidine tag. The NGAL is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Recombinant Human Lipocalin-2 also called Neutrophil Gelatinase Associated Lipocalin (NGAL) belongs to a family of lipocans which include 25 proteins (including α1-microglobulin and β-lactoglobulin), which are characterized by their ability to bind small lipophilic substances in their hydrophobic core. They thereby serve as transporters of substances like retinal, biliverdins & prostaglandins. There are indications that NGAL is involved in modulation of the inflammatory response and is found in the plasma of patients after stroke.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95% as determined by SDS-PAGE. Single band on Western Blot.
• Formulation: Lipocalin-2 (0.35 mg/ml) is supplied in PBS, 50% glycerol.
• Application: NGAL can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.
• Storage Conditions: Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) [ Homo sapiens ]
• Synonyms: matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); GELB; CLG4B; MMP-9; MANDP2; MMP9; matrix metalloproteinase 9; type V collagenase; macrophage gelatinase; matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase); Gelatinase B; 92 kDa type IV collagenase; 92 kDa gelatinase; OTTHUMP00000031674; EC 3.4.24.35
• Gene ID: 4318
• mRNA Refseq: NM_004994
• Protein Refseq: NP_004985
• MIM: 120361
• UniProt ID: P14780
• Pathway: Leukocyte transendothelial migration; Pathways in cancer; Bladder cancer
• Function: metalloendopeptidase activity; calcium ion binding; collagen binding; peptidase activity; zinc ion binding