Recombinant Human MMP20 Protein, His-tagged

• Cat.No.: MMP20-541H
• Product Overview: Recombinant Human MMP20 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.
• Source: E. coli
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 52 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MMP20 matrix metallopeptidase 20 [ Homo sapiens ]
• Official Symbol: MMP20
• Synonyms: MMP20; matrix metallopeptidase 20; matrix metalloproteinase 20 (enamelysin); matrix metalloproteinase-20; enamelysin; enamel metalloproteinase; AI2A2; MMP-20
• Gene ID: 9313
• mRNA Refseq: NM_004771
• Protein Refseq: NP_004762
• MIM: 604629
• UniProt ID: O60882