Recombinant Human MLXIPL, GST-tagged

• Cat.No.: MLXIPL-111H
• Product Overview: Recombinant Human MLXIPL (603 aa. - 700 aa.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ system.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
• Molecular Mass: 36.52 kDa
• Sequence: PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI
• Purification: Glutathione Sepharose 4 Fast Flow
• Storage buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Applications: ELISA; WB
• Storage: Store at -80 °C. Aliquot to avoid repeated freezing and thawing.
• Note: Best use within three months from the date of receipt of this protein.
• OfficialSymbol: MLXIPL

Gene Information

• Gene Name: MLXIPL MLX interacting protein-like [ Homo sapiens ]
• Synonyms: MLX interacting protein-like; MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14; MLXIPL; williams-Beuren syndrome chromosomal region 14 protein; Mlx interactor; MLX-interacting protein-like; class D basic helix-loop-helix protein 14; Williams Beuren syndrome chromosome region 14; carbohydrate response element binding protein; carbohydrate-responsive element-binding protein; WS basic-helix-loop-helix leucine zipper protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2
• Gene ID: 51085
• mRNA Refseq: NM_032951
• Protein Refseq: NP_116569
• MIM: 605678
• UniProt ID: Q9NP71
• Chromosome Location: 7q11.23
• Pathway: Integration of energy metabolism
• Function: transcription repressor activity; transcription factor binding; transcription factor activity; transcription activator activity; protein homodimerization activity; protein heterodimerization activity; DNA binding