Recombinant Human Mitogen-Activated Protein Kinase 9, GST-Tagged

• Cat.No.: MAPK9-1052H
• Product Overview: Recombinant full-length human MAPK9 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: MAPK9-1052H
• Description: MAPK9 is a member of the JNK family that acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MAPK9 targets specific transcription factors, and mediates immediate-early gene expression in response to various cell stimuli. Both UV radiation and the proinflammatory cytokine TNFα can induce MAPK9. MAPK9 play a main role in the regulation of regional specific apoptosis during early brain development and providing protection against autoimmune diabetes.
• Applications: Kinase Assay, Western Blot
• Molecular Weight: 70 kDa
• Expression System: Sf9 insect cells using baculovirus.
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
• Specific Activity: 3.3 nmol/min/mg
• Purity: > 95 %
• Concentration: 0.1 ug/ul
• Sequences: Full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; RIG-I-like receptor signaling pathway; T cell receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway

Gene Information

• Gene Name: MAPK9 mitogen-activated protein kinase 9 [ Homo sapiens ]
• Official Symbol: MAPK9
• Synonyms: MAPK9; JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; JNK2BETA; p54aSAPK; JNK2ALPHA; Jun kinase; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase JNK2; mitogen-activated protein kinase 9 isoform JNK2 alpha2; mitogen-activated protein kinase 9; EC 2.7.11.24; Mitogen-activated protein kinase 9; Stress-activated protein kinase JNK2; OTTHUMP00000161542; OTTHUMP00000161543
• Gene ID: 5601
• mRNA Refseq: NM_139068
• Protein Refseq: NP_620707
• MIM: 602896
• UniProt ID: P45984
• Chromosome Location: 5q35
• Function: ATP binding; JUN kinase activity; MAP kinase activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity