Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged

Cat. No. :

MAPK12-1264H

Description :

MAPK12is an enzyme that in humans is encoded by the MAPK12 gene. Activation ofmembers of the mitogen-activated protein kinase family is a major mechanismfor transduction of extracellular signals. Stress-activated protein kinasesare one subclass of MAP kinases. The protein encoded by this gene functionsas a signal transducer during differentiation of myoblasts to myotubes.

Source :

Insect cells

Species :

Human

Form :

Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.25 mM EDTA + 0.01% Triton X-100 + 2 mMDTT + 50% glycerol.

Molecular Weight :

46 kDa

Storage :

Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.

OfficialSymbol :

MAPK12

nullValue_other :

Function

ATP binding; MAP kinaseactivity; MAP kinase kinase activity; MP kinase activity; nucleotide binding;protein binding; protein serine/threonine kinase activity; proteinserine/threonine kinase activity; transferase activity

Full Length :

Full L.

Gene Name	MAPK12mitogen-activated protein kinase 12 [ Homosapiens ]
Synonyms	MAPK12;mitogen-activated protein kinase 12; ERK3; ERK6; ERK-6; SAPK3;PRKM12; SAPK-3; P38GAMMA; stress-activated proteinkinase 3; mitogen-activated protein kinase 3; EC 2.7.11.24; MAPkinase 12; OTTHUMP00000028548; OTTHUMP00000196671; MAP kinase p38 gamma;extracellular signal-regulated kinase 6; mitogen-activated protein kinase p38gamma
Gene ID	6300
mRNA Refseq	NM_002969
Protein Refseq	NP_002960
MIM	602399
UniProt ID	P53778
Chromosome Location	22q13.33
Pathway	Amyotrophic lateral sclerosis(ALS); Epithelial cell signaling in Helicobacter pylori infection; Fc epsilonRI signaling pathway; GnRH signaling pathway; Leukocyte transendothelialmigration; MAPK signaling pathway; Neurotrophin signaling pathway; RIG-I-likereceptor signaling pathway; T cell receptor signaling pathway; Toll-likereceptor signaling pathway; VEGF signaling pathway; Signalling by NGF

IL2-255E	Active Recombinant Equine Interleukin 2	+Inquiry
IL23A-239B	Active Recombinant Bovine Interleukin 23, Alpha Subunit P19	+Inquiry
FMO5-717H	Recombinant Human Flavin Containing Monooxygenase 5	+Inquiry
FMO3-718H	Recombinant Human Flavin Containing Monooxygenase 3	+Inquiry
FMO1-719H	Recombinant Human Flavin Containing Monooxygenase 1	+Inquiry