Recombinant Human Mitogen-Activated Protein Kinase 12, His-tagged

• Cat.No.: MAPK12-1264H
• Product Overview: Recombinant human full length MAPK12,His-tagged is expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: MAPK12is an enzyme that in humans is encoded by the MAPK12 gene. Activation ofmembers of the mitogen-activated protein kinase family is a major mechanismfor transduction of extracellular signals. Stress-activated protein kinasesare one subclass of MAP kinases. The protein encoded by this gene functionsas a signal transducer during differentiation of myoblasts to myotubes.
• Form: Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.25 mM EDTA + 0.01% Triton X-100 + 2 mMDTT + 50% glycerol.
• Molecular Weight: 46 kDa
• Storage: Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: MAPK12
• Function: ATP binding; MAP kinaseactivity; MAP kinase kinase activity; MP kinase activity; nucleotide binding;protein binding; protein serine/threonine kinase activity; proteinserine/threonine kinase activity; transferase activity
• Full Length: Full L.

Gene Information

• Gene Name: MAPK12mitogen-activated protein kinase 12 [ Homosapiens ]
• Synonyms: MAPK12;mitogen-activated protein kinase 12; ERK3; ERK6; ERK-6; SAPK3;PRKM12; SAPK-3; P38GAMMA; stress-activated proteinkinase 3; mitogen-activated protein kinase 3; EC 2.7.11.24; MAPkinase 12; OTTHUMP00000028548; OTTHUMP00000196671; MAP kinase p38 gamma;extracellular signal-regulated kinase 6; mitogen-activated protein kinase p38gamma
• Gene ID: 6300
• mRNA Refseq: NM_002969
• Protein Refseq: NP_002960
• MIM: 602399
• UniProt ID: P53778
• Chromosome Location: 22q13.33
• Pathway: Amyotrophic lateral sclerosis(ALS); Epithelial cell signaling in Helicobacter pylori infection; Fc epsilonRI signaling pathway; GnRH signaling pathway; Leukocyte transendothelialmigration; MAPK signaling pathway; Neurotrophin signaling pathway; RIG-I-likereceptor signaling pathway; T cell receptor signaling pathway; Toll-likereceptor signaling pathway; VEGF signaling pathway; Signalling by NGF