Recombinant Human MIA protein

• Cat.No.: MIA-196H
• Product Overview: Recombinant Human MIA was expressed in E. coli.

Specification

• Description: MIA is a secreted, regulatory protein produced mainly by chondrocytes and malignant melanoma cells. This protein induces the metastasis of cancer cells by indirectly causing the detachment of melanoma cells from the surrounding extracellular matrix. MIA levels are now measured and used as a diagnostic tool for melanoma metastasis and rheumatoid arthritis.
• Source: E. coli
• Species: Human
• Form: Lyophilized from a 0.2 μm filtered solution in PBS
• Molecular Mass: 12.4 kDa
• Endotoxin: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: 95%
• Applications: Cell Assay
• Storage: The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade- 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS
• Tag: Non

Gene Information

• Gene Name: MIA melanoma inhibitory activity [ Homo sapiens ]
• Official Symbol: MIA
• Synonyms: MIA; melanoma inhibitory activity; melanoma-derived growth regulatory protein; CD RAP; CD-RAP
• Gene ID: 8190
• mRNA Refseq: NM_001202553
• Protein Refseq: NP_001189482
• MIM: 601340
• UniProt ID: Q16674
• Chromosome Location: 19q13.32-q13.33
• Function: growth factor activity