Recombinant Human MGMT Protein, MYC/DDK-tagged
Cat.No. : | MGMT-1238H |
Product Overview : | Recombinant human MGMT protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. [UniProtKB/Swiss-Prot Function] |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 24.9 kDa |
Purity : | >50 ug/mL as determined by microplate BCA method |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | MGMT O-6-methylguanine-DNA methyltransferase [ Homo sapiens ] |
Official Symbol | MGMT |
Synonyms | O6-methylguanine-DNA methyltransferase; OTTHUMP00000020741; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA methyltransferase |
Gene ID | 4255 |
mRNA Refseq | NM_002412 |
Protein Refseq | NP_002403 |
MIM | 156569 |
UniProt ID | P16455 |
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Not For Human Consumption!
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