Recombinant Human MGLL Protein, His-tagged

• Cat.No.: MGLL-103H
• Product Overview: Active full length human recombinant C-terminal His-tagged MGLL protein (2-313) was expressed in E. coli.

Specification

• Description: This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 39 kDa
• Protein length: 2-313
• Purity: ≥95% as determined by SDS-PAGE
• Unit Definition: One unit of enzyme will produce 1 μmol of 4-nitrophenol per minute at 25 centigrade in 10 mM Tris, pH 7.2, 1 mM EDTA using 1.5 μM 4-nitrophenylacetate as substrate, measured by absorbance at 412 nm.
• Stability: ≥ 2 year
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 7.4, with 100 mM sodium chloride, 5 mM MgCl2, 0.1% CHAPS, and 25% glycerol

Gene Information

• Gene Name: MGLL monoglyceride lipase [ Homo sapiens (human) ]
• Official Symbol: MGLL
• Synonyms: MGLL; monoglyceride lipase; MGL; HUK5; MAGL; HU-K5; monoglyceride lipase; lysophospholipase homolog; monoacylglycerol lipase; EC 3.1.1.23
• Gene ID: 11343
• mRNA Refseq: NM_007283
• Protein Refseq: NP_009214
• MIM: 609699
• UniProt ID: Q99685