Recombinant Human MET

• Cat.No.: MET-2394H
• Product Overview: Recombinant Human MET(aa 18-217) is expressed inE.coli.MW=50kDa.

Specification

• Cat. No.: MET-2394H
• Description: The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.
• Source: E. coli.
• Presentation: 100μl purified human MET protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
• Application: ELISA, Inhibition Assays, Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 50kDa including GST.
• Storage: Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
• Tag: Non
• Protein length: 18-217 a.a.

Gene Information

• Gene Name: MET met proto-oncogene (hepatocyte growth factor receptor) [ Homo sapiens ]
• Synonyms: MET; met proto-oncogene (hepatocyte growth factor receptor); AUTS9; HGFR; RCCP2; c-Met; HGF receptor; OTTHUMP00000069168; SF receptor; met proto-oncogene; met proto-oncogene tyrosine kinase; oncogene MET; scatter factor receptor; EC 2.7.10.1; HGF/SF receptor; met proto-oncogene
• Gene ID: 4233
• mRNA Refseq: NM_000245
• Protein Refseq: NP_000236
• MIM: 164860
• UniProt ID: P00533
• Chromosome Location: 7q31
• Pathway: Adherens junction; Axon guidance; Colorectal cancer; Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Focal adhesion; Melanoma; Renal cell carcinoma
• Function: Cell proliferation; cell surface receptor linked signal transduction; multicelllular organismal development; protein amino acid phosphorylation