Recombinant Human Membrane Metallo-endopeptidase, His-tagged

• Cat.No.: MME-632H
• Product Overview: Recombinant Human Membrane Metallo-endopeptidase is produced inSf9 cellsandfused at the N-terminus to a His-tag. MW= 85 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: His
• Description: MME, or 2,4-dimethoxy-5-ethoxyamphetamine, is a lesser-known psychedelic drug. It is a dimethoxy-ethoxy analog of TMA-2. MME was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 40 mg, and the duration listed as 6–10 hours. Shulgin gives MME a ++ on the Shulgin Rating Scale. Very little data exists about the pharmacological properties, metabolism, and toxicity of MME.
• Concentration: 0.23 μg/μl.
• Purity: ≥95% (SDS-PAGE).
• Formulation: Liquid. In 50mM TRIS, pH 8.0. containing 300mM sodium chloride and 20% glycerol.
• Specific Activity: 1140 pmol/min/μg.
• Application: Study enzyme kinetics, cleave target substrates, and screen for inhibitors.
• Storage And Stability: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: MME membrane metallo-endopeptidase [ Homo sapiens ]
• Synonyms: MME; membrane metallo-endopeptidase; atriopeptidase; common acute lymphocytic leukemia antigen; enkephalinase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; neprilysin; neutral endopeptidase 24.11; EC 3.4.24.11
• Gene ID: 4311
• mRNA Refseq: NM_000902
• Protein Refseq: NP_000893
• MIM: 120520
• UniProt ID: P08473
• Chromosome Location: 3q25.1-q25.2
• Pathway: Alzheimer"s disease; Hematopoietic cell lineage; Renin-angiotensin system
• Function: metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; peptide binding; zinc ion binding