Recombinant human MDS1, His-tagged

• Cat.No.: MDS1-2426H
• Product Overview: Recombinant human MDS1 protein, fused to His-tag at N-terminus, was expressed in E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 21.1kDa (192aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAPIYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS
• Purity: >85 % by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MDS1 myelodysplasia syndrome 1 [ Homo sapiens ]
• Official Symbol: MDS1
• Synonyms: MDS1; myelodysplasia syndrome 1; myelodysplasia syndrome-associated protein 1; PRDM3; MDS1-EVI1
• Gene ID: 4197
• Chromosome Location: -