Recombinant Human MBL2 protein, His & GST-tagged

• Cat.No.: MBL2-575H
• Product Overview: Recombinant Human MBL2 (P11226) aa. (Leu130~Ile248) fused with His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43kDa; Accurate Molecular Mass: 43kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Leu130~Ile248
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >98%
• Characteristic: Isoelectric point is 5.8.
• Applications: Cell culture; Activity Assays; In vivo assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: MBL2 mannose binding lectin 2 [ Homo sapiens (human) ]
• Official Symbol: MBL2
• Synonyms: MBL2; mannose binding lectin 2; MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC; mannose-binding protein C; collectin-1; mannan-binding lectin; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect)
• Gene ID: 4153
• mRNA Refseq: NM_000242.2
• Protein Refseq: NP_000233.1
• UniProt ID: P11226