Recombinant human MBIP, His-tagged

• Cat.No.: MBIP-2464H
• Product Overview: Recombinant human MBIP protein, fused to His-tag at N-terminus, was expressed in E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MBIP inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. This protein is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 41.7kDa (367aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAATEL NRPSSGDRNL ERRCRPNLSR EVLYEIFRSL HTLVGQLDLR DDVVKITIDW NKLQSLSAFQPALLFSALEQ HILYLQPFLA KLQSPIKEEN TTAVEEIGRT EMGNKNEVND KFSIGDLQEE EKHKESDLRD VKKTQIHFDP EVVQIKAGKA EIDRRISAFI ERKQAEINEN NVREFCNVID CNQENSCART DAIFTPYPGF KSHVKVSRVV NTYGPQTRPE GIPGSGHKPN SMLRDCGNQAVEERLQNIEA HLRLQTGGPV PRDIYQRIKK LEDKILELEG ISPEYFQSVS FSGKRRKVQP PQQNYSLAEL DEKISALKQA LLRKSREAES MATHHLP
• Purity: >85 % by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MBIP MAP3K12 binding inhibitory protein 1 [ Homo sapiens ]
• Official Symbol: MBIP
• Synonyms: MBIP; MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MUK-binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein
• Gene ID: 51562
• mRNA Refseq: NM_001144891
• Protein Refseq: NP_001138363
• MIM: 609431
• UniProt ID: Q9NS73
• Chromosome Location: 14q13.2
• Function: identical protein binding; protein binding; protein kinase inhibitor activity