Recombinant Human MASP1 Protein (His20-Arg728), C-His tagged
Cat.No. : | MASP1-3743H |
Product Overview : | Recombinant human MASP1 (His20-Arg728) fused with the C-terminal His tag was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | Mammalian Cells |
Tag : | His |
Protein Length : | His20-Arg728 |
Description : | This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 78.1 kDa |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name | MASP1 MBL associated serine protease 1 [ Homo sapiens (human) ] |
Official Symbol | MASP1 |
Synonyms | MASP1; MBL associated serine protease 1; 3MC1; MAP1; MASP; RaRF; CRARF; MAP-1; MASP3; MAp44; PRSS5; CRARF1; MASP-3; mannan-binding lectin serine protease 1; C4/C2 activating component of Ra-reactive factor; Ra-reactive factor serine protease p100; complement factor MASP-3; complement-activating component of Ra-reactive factor; mannan binding lectin serine peptidase 1; mannose-associated serine protease 1; mannose-binding lectin-associated serine protease 1; mannose-binding protein-associated serine protease; serine protease 5; EC 3.4.21.- |
Gene ID | 5648 |
mRNA Refseq | NM_139125 |
Protein Refseq | NP_624302 |
MIM | 600521 |
UniProt ID | P48740 |
◆ Recombinant Proteins | ||
MASP1-3744H | Recombinant Human MASP1 Protein (His20-Pro434), N-His tagged | +Inquiry |
MASP1-3743H | Recombinant Human MASP1 Protein (His20-Arg728), C-His tagged | +Inquiry |
MASP1-138H | Active Recombinant Human MASP1 protein, His-tagged | +Inquiry |
MASP1-9576M | Recombinant Mouse MASP1 Protein | +Inquiry |
MASP1-137H | Recombinant Human MASP1, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
MASP1-4461HCL | Recombinant Human MASP1 293 Cell Lysate | +Inquiry |
MASP1-4460HCL | Recombinant Human MASP1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All MASP1 Products
Required fields are marked with *
My Review for All MASP1 Products
Required fields are marked with *
0
Inquiry Basket