Recombinant Human MAPK6 Protein (M9-I327), His tagged

• Cat.No.: MAPK6-0109H
• Product Overview: Recombinant Human 6His-TEV-S-ERK3(M9-I327) (L290V) Protein was expressed in E. coli.

Specification

• Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Protein length: M9-I327
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: MAPK6 mitogen-activated protein kinase 6 [ Homo sapiens (human) ]
• Official Symbol: MAPK6
• Synonyms: MAPK6; mitogen-activated protein kinase 6; PRKM6; ERK3; HsT17250; p97MAPK; ERK-3; MAPK 6; p97-MAPK; MAP kinase 6; MAP kinase isoform p97; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; DKFZp686F03189
• Gene ID: 5597
• mRNA Refseq: NM_002748
• Protein Refseq: NP_002739
• MIM: 602904
• UniProt ID: Q16659