Recombinant Human MAP4K5 Protein, His tagged

• Cat.No.: MAP4K5-001H
• Product Overview: Recombinant Human MAP4K5 Protein with C-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
• Source: E. coli
• Species: Human
• Tag: C-His
• Protein length: 395-484 aa
• Molecular Mass: 11 kDa
• AA Sequence: MKPRISSYPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKNDKRDFPKPAINHHHHHHHH
• Endotoxin: < 1 EU/μg by LAL
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH7.4
• Concentration: 1 mg/mL by BCA

Gene Information

• Gene Name: MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 [ Homo sapiens (human) ]
• Official Symbol: MAP4K5
• Synonyms: MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5; GCKR; germinal center kinase related; KHS; KHS1; MEKKK 5; MEK kinase kinase 5; germinal center kinase-related; MAPK/ERK kinase kinase kinase 5; kinase homologous to SPS1/STE20; MAPKKKK5
• Gene ID: 11183
• mRNA Refseq: NM_006575
• Protein Refseq: NP_006566
• MIM: 604923
• UniProt ID: Q9Y4K4