Recombinant Human MACC1 Protein, MYC/DDK-tagged

• Cat.No.: MACC1-177H
• Product Overview: Recombinant human MACC1 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 96.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MACC1, MET transcriptional regulator [ Homo sapiens ]
• Official Symbol: MACC1
• Synonyms: 7A5; SH3BP4L
• Gene ID: 346389
• mRNA Refseq: NM_182762.3
• Protein Refseq: NP_877439.3
• MIM: 612646
• UniProt ID: Q6ZN28