Recombinant Human LTB4R

• Cat.No.: LTB4R-27118TH
• Product Overview: Recombinant full length Human Leukotriene B4 Receptor with N terminal FLAG tag and C terminal His tag co-expressed with inhibitory G-protein Gia1b1g2, prepared from Sf9 insect cells triple-infected with Leukotriene B4 Receptor, Gia1 and Gb1g2 encoding

Specification

• Species: Human
• Tag: His&Flag
• Description: BLTR (Leukotriene B4 receptor) is a seven transmembrane-domain (7TM), G protein-coupled receptor (GPCR). BLTR is a potent chemoattractant active on multiple leukocytes, including neutrophils, macrophages, and eosinophils. BLTR is involved in the pathogenesis of a wide variety ofhuman inflammatory diseases. Therefore, the BLTR represents an attractive target for therapeutic intervention.
• Conjugation: FLAG,His
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: LTB4R leukotriene B4 receptor [ Homo sapiens ]
• Official Symbol: LTB4R
• Synonyms: LTB4R; leukotriene B4 receptor; CMKRL1, GPR16, P2RY7; leukotriene B4 receptor 1; BLTR; LTB4R1; P2Y7
• Gene ID: 1241
• mRNA Refseq: NM_001143919
• Protein Refseq: NP_001137391
• MIM: 601531
• Uniprot ID: Q15722
• Chromosome Location: 14q11.2-q12
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem
• Function: leukotriene B4 receptor activity; leukotriene receptor activity; nucleotide binding; receptor activity; signal transducer activity