Recombinant Human Low Density Lipoprotein Receptor-Related Protein Associated Protein 1, His-tagged

Cat. No. :	LRPAP1-1384H
Description :	LRPAP1,also known as alpha-2-macroglobulin receptor-associated protein, belongs tothe alpha-2-MRAP family. This protein interacts withLRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present onthe cell surface forming a complex with the alpha 2 macroglobulin receptorheavy and light chains In complex with the alpha 2 MR or gp330, it may havesome role in the pathogenesis of membrane glomerular nephritis.
Form :	Liquid. 20mM Tris-HClbuffer (pH8.0) containing 20% glycerol 1mM DTT.
Molecular Weight :	40.4 kDa(348aa), confirmed by MALDI-TOF.
Purity :	> 90%by SDS - PAGE
Concentration :	1.0mg/ml (determined by Bradford assay)
Sequences of aminoacids :	MGSSHHHHHHSSGLVPRGSH MGSHMYSREK NQPKPSPKRE SGEEFRMEKL NQLWEKAQRLHLPPVRLAEL HADLKIQERD ELAWKKLKLD GLDEDGEKEARLIRNLNVIL AKYGLDGKKD ARQVTSNSLS GTQEDGLDDP RLEKLWHKAK TSGKFSGEEL DKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDL SDIKGSVLHS RHTELKEKLR SINQGLDRLR RVSHQGYSTE AEFEEPRVID LWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLE IAHEKLRHAE SVGDGERVSR SREKHALLEG RTKELGYTVK KHLQDLSGRI SRARHNEL
Storage :	Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Name	LRPAP1 low density lipoproteinreceptor-related protein associated protein 1 [ Homo sapiens ]
Official Symbol	LRPAP1
Synonyms	LRPAP1; low density lipoproteinreceptor-related protein associated protein 1; RAP; MRAP; A2RAP; HBP44;A2MRAP; MGC138272; alpha-2-macroglobulin receptor-associated protein;alpha-2-MRAP; OTTHUMP00000115346; lipoprotein receptor associated protein;alpha-2-macroglobulin receptor-associated protein 1; low density lipoproteinreceptor-related protein-associated protein 1; low densitylipoprotein-related protein-associated protein 1 (alpha-2-macroglobulinreceptor-associated protein 1)
Gene ID	4043
mRNA Refseq	NM_002337
Protein Refseq	NP_002328
MIM	104225
UniProt ID	P30533
Chromosome Location	4p16.3
Pathway	Lissencephaly gene (LIS1) in neuronalmigration and development; Reelin signaling pathway; Signaling eventsmediated by the Hedgehog family
Function	asialoglycoprotein receptor activity;heparin binding; lipase binding; low-density lipoprotein particle receptorbinding; receptor antagonist activity; unfolded protein binding;very-low-density lipoprotein particle receptor binding

COA

Cat.No. :	LRPAP1-1384H
Product Overview :	Recombinant humanLRPAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.