Recombinant Human Lnterleukin 32, His-tagged

• Cat.No.: IL32-108H
• Product Overview: Recombinant human Interleukin 32, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography,19.1 kDa (168aa).

Specification

• Cat. No.: IL32-108H
• Description: Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNFα and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NFκB and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK
• Formulation: Liquid. In20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined byBradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: interleukin 32 [ Homo sapiens ]
• Synonyms: IL32; interleukin 32;NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor
• Gene ID: 9235
• mRNA Refseq: NM_001012631
• Protein Refseq: NP_001012649
• MIM: 606001
• UniProt ID: P24001
• Chromosome Location: 16p13.3
• Function: cytokine activity