Recombinant Human LMNB2 Protein, MYC/DDK-tagged

• Cat.No.: LMNB2-737H
• Product Overview: Recombinant human LMNB2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 67.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: lamin B2[ Homo sapiens ]
• Official Symbol: LMNB2
• Synonyms: EPM9; LAMB2; LMN2
• Gene ID: 84823
• mRNA Refseq: NM_032737.3
• Protein Refseq: NP_116126
• MIM: 150341
• UniProt ID: Q03252