Recombinant Human LMAN1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | LMAN1-6462H |
Product Overview : | LMAN1 MS Standard C13 and N15-labeled recombinant protein (NP_005561) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. |
Molecular Mass : | 57.5 kDa |
AA Sequence : | MAGSRQRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSLSETVRLVSGMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVHFIIFVVVQTVLFIGYIMYRSQQEAAAKKFFTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | LMAN1 lectin, mannose binding 1 [ Homo sapiens (human) ] |
Official Symbol | LMAN1 |
Synonyms | LMAN1; lectin, mannose-binding, 1; coagulation factor V factor VIII combined deficiency, F5F8D; protein ERGIC-53; endoplasmic reticulum golgi intermediate compartment protein 53; ERGIC 53; ERGIC53; FMFD1; gp58; MCFD1; MR60; intracellular mannose specific lectin; intracellular mannose-specific lectin MR60; ER-Golgi intermediate compartment 53 kDa protein; endoplasmic reticulum-golgi intermediate compartment protein 53; F5F8D; ERGIC-53; |
Gene ID | 3998 |
mRNA Refseq | NM_005570 |
Protein Refseq | NP_005561 |
MIM | 601567 |
UniProt ID | P49257 |
◆ Recombinant Proteins | ||
LMAN1-3423R | Recombinant Rat LMAN1 Protein | +Inquiry |
LMAN1-2348R | Recombinant Rhesus Macaque LMAN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LMAN1-7896H | Recombinant Human LMAN1 protein, His-tagged | +Inquiry |
LMAN1-1301H | Recombinant Human LMAN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LMAN1-2528R | Recombinant Rhesus monkey LMAN1 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
LMAN1-4719HCL | Recombinant Human LMAN1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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