Recombinant Human LGALS14 Protein (Ser2-Asp139), N-His tagged, Animal-free, Carrier-free

• Cat.No.: LGALS14-258H
• Product Overview: Recombinant Human LGALS14 Protein (Ser2-Asp139) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Galectin-14 (Gal-14) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-14 is like Galectin-13, which is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The galectin-14 enhances trophoblast migration and invasion via promoting the expression of MMP-9 and N-cadherin in the Akt pathway. Furthermore, galectin-14 stimulates the production of IL-8 in non-activated T cells, which associate with angiogenesis at the maternal-fetal interface.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 16.9 kDa.
  The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).
• Protein length: Ser2-Asp139
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: LGALS14 lectin, galactoside-binding, soluble, 14 [ Homo sapiens (human) ]
• Official Symbol: LGALS14
• Synonyms: LGALS14; lectin, galactoside-binding, soluble, 14; placental protein 13-like; CLC2; PPL13; gal-14; galectin-14; Charcot-Leyden crystal protein 2; placental protein 13-like protein; MGC22235
• Gene ID: 56891
• mRNA Refseq: NM_020129
• Protein Refseq: NP_064514
• MIM: 607260
• UniProt ID: Q8TCE9