Recombinant Human Leucine Zipper, Down-Regulated In Cancer 1-Like, His-tagged

• Cat.No.: LDOC1L-6945H
• Product Overview: Recombinant human LDOC1L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: LDOC1L belongs to the LDOC1 family. LDOC1 is a nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. LDOC1L is thought to regulate the transcriptional response mediated by the nuclear factor kB.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF, 1mM EDTA.
• Molecular Mass: 28.7 kDa (263aa), confirmed by MALDI-TOF
• Protein length: 1-239aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVQPQT SKAESPALAA SPNAQMDDVI DTLTSLRLTN SALRREASTL RAEKANLTNM LESVMAELTL LRTRARIPGA LQITPPISSI TSNGTRPMTT PPTSLPEPFS GDPGRLAGFL MQMDRFMIFQ ASRFPGEAER VAFLVSRLTG EAEKWAIPHM QPDSPLRNNY QGFLAELRRT YKSPLRHARR AQIRKTSASN RAVRERQMLC RQLASAGTGP CPVHPASNGT SPAPALPARA RNL
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: LDOC1L leucine zipper, down-regulated in cancer 1-like [ Homo sapiens ]
• Official Symbol: LDOC1L
• Synonyms: LDOC1L; leucine zipper, down-regulated in cancer 1-like; protein LDOC1L; dJ1033E15.2; DKFZp761O17121; Mar6; Mart6; mammalian retrotransposon-derived protein 6; leucine zipper protein down-regulated in cancer cells-like
• Gene ID: 84247
• mRNA Refseq: NM_032287
• Protein Refseq: NP_115663
• UniProt ID: Q6ICC9
• Chromosome Location: 22q13.3