Recombinant Human Leucine Rich Repeat Containing 32, Fc Chimera

• Cat.No.: LRRC32-2158H
• Product Overview: Recombinant Human LRRC32 (aa 20-627) produced inCHO cellsis fused to the Fc portion of human IgG1.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 20-627 a.a.
• Description: A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold.[1][2] It is composed of repeating 20-30 amino acid stretches that are unusually rich in the hydrophobic amino acid leucine. Typically, each repeat unit has beta strand-turn-alpha helix structure, and the assembled domain, composed of many such repeats, has a horseshoe shape with an interior parallel beta sheet and an exterior array of helices. One face of the beta sheet and one side of the helix array are exposed to solvent and are therefore dominated by hydrophilic residues. The region between the helices and sheets is the protein"s hydrophobic core and is tightly sterically packed with leucine residues.Leucine-rich repeats are frequently involved in the formation of protein-protein interactions.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Lyophilized. Contains PBS.
• Concentration: 1mg/ml (after reconstitution).
• Reconstitution: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; BioWhittaker).
• Stability: Stable for at least 6 months after receipt when stored at -20°C.

Gene Information

• Gene Name: LRRC32 leucine rich repeat containing 32 [ Homo sapiens ]
• Synonyms: LRRC32; leucine rich repeat containing 32; GARP; D11S833E; leucine-rich repeat-containing protein 32; garpin; glycoprotein A repetitions predominant; OTTHUMP00000200860; GARP protein
• Gene ID: 2615
• mRNA Refseq: NM_001128922
• Protein Refseq: NP_001122394
• MIM: 137207
• UniProt ID: Q14392
• Chromosome Location: 11q13.5-q14
• Function: protein binding