Recombinant Human LDHD, GST-tagged

• Cat.No.: LDHD-260H
• Product Overview: Recombinant Human LDHD(1 a.a. - 507 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
• Molecular Mass: 81.3 kDa
• AA Sequence: MARLLRSATWELFPWRGYCSQKAKGELCRDFVEALKAVVGGSHVSTAAVVREQHGRDESVHRCEPPDAVVWPQNV EQVSRLAALCYRQGVPIIPFGTGTGLEGGVCAVQGGVCVNLTHMDRILELNQEDFSVVVEPGVTRKALNAHLRDS GLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYS PCVSLGRRKSAAGYNLTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHILQAAVPVARIE FLDEVMMDACNRYSKLNCLVAPTLFLEFHGSQQALEEQLQRTEEIVQQNGASDFSWAKEAEERSRLWTARHNAWY AALATRPGCKGYSTDVCVPISRLPEIVVQTKEDLNASGLTGSIVGHVGDGNFHCILLVNPDDAEELGRVKAFAEQ LGRRALALHGTCTGEHGIGMGKRQLLQEEVGAVGVETMRQLKAVLDPQGLMNPGKVL
• Applications: ELISA; WB-Re; AP; Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80ºC. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LDHD lactate dehydrogenase D [ Homo sapiens (human) ]
• Official Symbol: LDHD
• Synonyms: LDHD; lactate dehydrogenase D; probable D-lactate dehydrogenase, mitochondrial; D-lactate dehydrogenase; DLD; MGC57726; NP_705690.2; EC 1.1.2.4; NP_919417.1
• Gene ID: 197257
• mRNA Refseq: NM_153486
• Protein Refseq: NP_705690
• MIM: 607490
• UniProt ID: Q86WU2
• Chromosome Location: 16q23.1
• Pathway: Metabolism of proteins; Mitochondrial protein import; Pyruvate metabolism; methylglyoxal degradation I
• Function: D-lactate dehydrogenase (cytochrome) activity; UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding