Recombinant Human LCMT2 protein, GST-tagged

• Cat.No.: LCMT2-188H
• Product Overview: Recombinant Human LCMT2 fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: LCMT2, also named tRNA wybutosine-synthesizing protein 4 (TYW4), is an S-adenosylmethionine (SAM)-dependent enzyme that involves in the final step of wybutosine biosynthesis pathway. Structural study revealed that TYW4 uses one catalytic site for both methylation and methoxycarbonylation process).
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: 90 kDa
• Purity: >70%
• Applications: Methyltransferase Assay
• Stability: 1 year at -70 centigrade from the date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05μg/μl

Gene Information

• Gene Name: LCMT2 leucine carboxyl methyltransferase 2 [ Homo sapiens ]
• Official Symbol: LCMT2
• Synonyms: LCMT2; leucine carboxyl methyltransferase 2; KIAA0547; MGC9534; PPM2; tRNA yW synthesizing protein 4; TYW4; tRNA-yW synthesizing protein 4; tRNA-Wybutosine-synthesizing protein 4; p21WAF1/CIP1 promoter-interacting protein; FLJ51321
• Gene ID: 9836
• mRNA Refseq: NM_014793
• Protein Refseq: NP_055608
• MIM: 611246
• UniProt ID: O60294
• Chromosome Location: 15q15.3
• Function: methyltransferase activity; protein binding; transferase activity