Recombinant Human KTELC1 Protein, MYC/DDK-tagged

• Cat.No.: KTELC1-1014H
• Product Overview: Recombinant human KTELC1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 46 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: protein O-glucosyltransferase 1 [ Homo sapiens ]
• Official Symbol: KTELC1
• Synonyms: CLP46, MDSRP, C3orf9, MDS010, hCLP46, KDELCL1, MGC32995
• Gene ID: 56983
• Protein Refseq: NP_689518
• MIM: 615618