Recombinant Human KRT17 protein, His & S-tagged

• Cat.No.: KRT17-1843H
• Product Overview: Recombinant Human KRT17 aa. (Ile252~Ala393 (Accession # Q04695)) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&S
• Protein Length: Ile252~Ala393
• Description: This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
• Form: Freeze-dried powder
• Molecular Mass: 22kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: KRT17 keratin 17 [ Homo sapiens (human) ]
• Official Symbol: KRT17
• Synonyms: Tnni1; troponin I, skeletal, slow 1; ssTnI; AI747285; 2700018B22Rik; troponin I, slow skeletal muscle; troponin I, slow-twitch isoform
• Gene ID: 3872
• mRNA Refseq: NM_000422.2
• Protein Refseq: NP_000413.1
• UniProt ID: Q04695