Description : |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
Source : |
Human cells |
Species : |
Human |
Tag : |
Flag |
Molecular Mass : |
24.9 kDa |
Endotoxin : |
Endotoxin level is < 0.1 ng/μg of protein (< 1 EU /μg) |
Purity : |
>90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : |
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
Storage Buffer : |
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |