Recombinant Human KIN, antigenic determinant of recA protein homolog (mouse), His-tagged

• Cat.No.: KIN-358H
• Product Overview: KIN17, 1-393aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-393 a.a.
• Description: DNA/RNA-binding protein KIN17, also known as KIN17, is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. KIN17 is ubiqutiously expressed with the highest levels of expression in muscle, heart and testis. SV40-transformed fibroblasts overexpress KIN17, which interacts with Large T antigen and reduces T-antigen-dependent DNA replication. Recombinant human KIN17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol
• Molecular Mass: 47.8 kDa (416aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGKSDFL TPKAIANRIK SKGLQKLRWY CQMCQKQCRD ENGFKCHCMS ESHQRQLLLA SENPQQFMDY FSEEFRNDFL ELLRRRFGTK RVHNNIVYNE YISHREHIHM NATQWETLTD FTKWLGREGL CKVDETPKGW YIQYIDRDPE TIRRQLELEK KKKQDLDDEE KTAKFIEEQV RRGLEGKEQE VPTFTELSRE NDEEKVTFNL SKGACSSSGA TSSKSSTLGP SALKTIGSSA SVKRKESSQS STQSKEKKKK KSALDEIMEI EEEKKRTART DYWLQPEIIV KIITKKLGEK YHKKKAIVKE VIDKYTAVVK MIDSGDKLKL DQTHLETVIP APGKRILVLN GGYRGNEGTL ESINEKTFSA TIVIETGPLK GRRVEGIQYE DISKLA
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: KIN KIN, antigenic determinant of recA protein homolog (mouse) [ Homo sapiens ]
• Official Symbol: KIN
• Synonyms: KIN; KIN, antigenic determinant of recA protein homolog (mouse); antigenic determinant of recA protein (mouse) homolog; DNA/RNA-binding protein KIN17; KIN17; binding to curved DNA; BTCD
• Gene ID: 22944
• mRNA Refseq: NM_012311
• Protein Refseq: NP_036443
• MIM: 601720
• UniProt ID: O60870
• Chromosome Location: 10p15-p14
• Function: DNA binding; RNA binding; double-stranded DNA binding; metal ion binding; zinc ion binding