Recombinant Human KIF5C Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KIF5C-3946H
• Product Overview: KIF5C MS Standard C13 and N15-labeled recombinant protein (NP_004513) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 109.3 kDa
• AA Sequence: MADPAECSIKVMCRFRPLNEAEILR GDKFIPKFKGDETVVIGQGKPYVFD RVLPPNTTQEQVYNACAKQIVKDVL EGYNGTIFAYGQTSSGKTHTMEGKL HDPQLMGIIPRIAHDIFDHIYSMDE NLEFHIKVSYFEIYLDKIRDLLDVS KTNLAVHEDKNRVPYVKGCTERFVS SPEEVMDVIDEGKANRHVAVTNMNE HSSRSHSIFLINIKQENVETEKKLS GKLYLVDLAGSEKVSKTGAEGAVLD EAKNINKSLSALGNVISALAEGTKT HVPYRDSKMTRILQDSLGGNCRTTI VICCSPSVFNEAETKSTLMFGQRAK TIKNTVSVNLELTAEEWKKKYEKEK EKNKTLKNVIQHLEMELNRWRNGEA VPEDEQISAKDQKNLEPCDNTPIID NIAPVVAGISTEEKEKYDEEISSLY RQLDDKDDEINQQSQLAEKLKQQML DQDELLASTRRDYEKIQEELTRLQI ENEAAKDEVKEVLQALEELAVNYDQ KSQEVEDKTRANEQLTDELAQKTTT LTTTQRELSQLQELSNHQKKRATEI LNLLLKDLGEIGGIIGTNDVKTLAD VNGVIEEEFTMARLYISKMKSEVKS LVNRSKQLESAQMDSNRKMNASERE LAACQLLISQHEAKIKSLTDYMQNM EQKRRQLEESQDSLSEELAKLRAQE KMHEVSFQDKEKEHLTRLQDAEEMK KALEQQMESHREAHQKQLSRLRDEI EEKQKIIDEIRDLNQKLQLEQEKLS SDYNKLKIEDQEREMKLEKLLLLND KREQAREDLKGLEETVSRELQTLHN LRKLFVQDLTTRVKKSVELDNDDGG GSAAQKQKISFLENNLEQLTKVHKQ LVRDNADLRCELPKLEKRLRATAER VKALESALKEAKENAMRDRKRYQQE VDRIKEAVRAKNMARRAHSAQIAKP IRPGHYPASSPTAVHAIRGGGGSSS NSTHYQKTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KIF5C kinesin family member 5C [ Homo sapiens (human) ]
• Official Symbol: KIF5C
• Synonyms: KIF5C; kinesin family member 5C; kinesin heavy chain isoform 5C; kinesin heavy chain neuron-specific 2; kinesin, heavy chain, neuron-specific; KINN; NKHC; NKHC2; NKHC-2; FLJ44735; KIAA0531; MGC111478
• Gene ID: 3800
• mRNA Refseq: NM_004522
• Protein Refseq: NP_004513
• MIM: 604593
• UniProt ID: O60282