Recombinant Human KHK, T7 -tagged

• Cat.No.: KHK-29896TH
• Product Overview: Recombinant full length protein (Human); T7 tag at N terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Description: This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Conjugation: T7
• Tissue specificity: Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the carbohydrate kinase pfkB family.
• Full Length: Full L.

Gene Information

• Gene Name: KHK ketohexokinase (fructokinase) [ Homo sapiens ]
• Official Symbol: KHK
• Synonyms: KHK; ketohexokinase (fructokinase); ketohexokinase
• Gene ID: 3795
• mRNA Refseq: NM_000221
• Protein Refseq: NP_000212
• MIM: 614058
• Uniprot ID: P50053
• Chromosome Location: 2p23.3-p23.2
• Pathway: Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Fructose catabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem
• Function: ATP binding; ketohexokinase activity; kinase activity; nucleotide binding; transferase activity