KHK
-
Official Full Name
ketohexokinase (fructokinase) -
Overview
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
KHK;ketohexokinase (fructokinase);ketohexokinase;hepatic fructokinase
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Human
- His
- T7
- Non
- DDK
- Myc
- Avi
- Fc
- GST
- Flag
Involved Pathway
KHK involved in several pathways and played different roles in them. We selected most pathways KHK participated on our site, such as Fructose and mannose metabolism,Fructose catabolism,Fructose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with KHK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | CPNE1,GLYAT,HSD17B11,ACOT9.1,APOEB,CRAT,ESRRA,MED25,PDZD11,ALOX5B.3 |
| sucrose degradation | GALM |
| Metabolism of carbohydrates | SLC2A3,OMD,OXSR1,SLC25A1A,SLC35B2,SLC25A10,GCKR,FMODA,Gpc2,HAS1 |
| Metabolic pathways | HLCS,ATP5G3,ATP5D,PEMT,ACY1,NT5C2A,FBP1,SRM,FLAD1,PET112L |
| Fructose and mannose metabolism | GMPPB,PFKFB4L,ALDOAA,AKR1B1L,AKR1B8,C12orf5,TSTA3,PFKMA,PMM1,ALDOB |
Protein Function
KHK has several biochemical functions, for example, ATP binding,ketohexokinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KHK itself. We selected most functions KHK had, and list some proteins which have the same functions with KHK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MBNL3,LCORL,ERBB3,RIOK3,MRC1,RELA,SLC22A6,BECN1,IL11,PLN |
| ATP binding | BCKDK,CHST13,OASL,BCS1L,STK25A,DCAMKL2,SGK2A,NEK10,ACTR1B,CSNK1DB |
Interacting Protein
KHK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KHK here. Most of them are supplied by our site. Hope this information will be useful for your research of KHK.
LHX9;14786024;DEDD;CD2BP2;SNRPB;LCN1;ARRB1;LYZ;ILK;RNPS1;CDK5RAP3
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