Recombinant Human Ketohexokinase (fructokinase)
Cat.No. : | KHK-905H |
Product Overview : | Ketohexokinase Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids and having a molecular mass of 32.7 kDa. |
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Species : | Human |
Source : | Human |
Tag : | Non |
Description : | Ketohexokinase catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, resulting in the utilization of ATP and creation of AMP. Ketohexokinase commences initial step in the metabolism of dietary fructose and is a significant regulator of hepatic glucose metabolism. Ketohexokinase is found in liver, renal cortex, and small intestine. |
Form : | The protein solution contains 1xPBS, pH 7.4 and 10 % glycerol. |
Purity : | Greater than 90.0 % as determined by SDS-PAGE. |
Amino acid sequence : | MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTIL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA). Avoid multiple freeze-thaw cycles. |
Gene Name | KHK ketohexokinase (fructokinase) [ Homo sapiens ] |
Official Symbol | KHK |
Synonyms | KHK; ketohexokinase (fructokinase); ketohexokinase; OTTHUMP00000122595; OTTHUMP00000122596; OTTHUMP00000200951; hepatic fructokinase |
Gene ID | 3795 |
mRNA Refseq | NM_000221 |
Protein Refseq | NP_000212 |
MIM | 614058 |
UniProt ID | P50053 |
Chromosome Location | 2p23.3-p23.2 |
Pathway | Fructose and mannose metabolism; Fructose catabolism; Metabolic pathways; Metabolism of carbohydrates |
Function | ATP binding; ketohexokinase activity; kinase activity; nucleotide binding; protein binding; transferase activity |
◆ Recombinant Proteins | ||
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◆ Cell & Tissue Lysates | ||
KHK-4985HCL | Recombinant Human KHK 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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