Recombinant Human KEL

• Cat.No.: KEL-26282TH
• Product Overview: Recombinant full length Human Blood Group Kell Antigen containing an N-terminal proprietary tag; Predicted MW 106.59 kDa

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 732 amino acids
• Description: This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
• Molecular Weight: 106.590kDa inclusive of tags
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLPVEGSR PWAVARRVLTAILILGLLLCFSVLLFYNFQNCGPRPCETS VCLDLRDHYLASGNTSVAPCTDFFSFACGRAKETNNSFQE LATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLA IEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQ YGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQ KIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITS RLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCL QATFTPMSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDF LQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPP MPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAM KLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMG ASEWALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIV QSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPP FFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGGCLACD NHALQEAHLCLKRHYAAFPLPSRTSFNDSLTFLENAADVG GLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQV MCRKPSPQDSHDTHSPPHLRVHGPLSSTPAFARYFRCARG ALLNPSSRCQLW
• Sequence Similarities: Belongs to the peptidase M13 family.

Gene Information

• Gene Name: KEL Kell blood group, metallo-endopeptidase [ Homo sapiens ]
• Official Symbol: KEL
• Synonyms: KEL; Kell blood group, metallo-endopeptidase; Kell blood group , Kell blood group, metalloendopeptidase; kell blood group glycoprotein; CD238; ECE3
• Gene ID: 3792
• mRNA Refseq: NM_000420
• Protein Refseq: NP_000411
• MIM: 613883
• Uniprot ID: P23276
• Chromosome Location: 7q33
• Function: metal ion binding; metalloendopeptidase activity; peptidase activity; protein binding