Recombinant Human KDM8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KDM8-6178H
• Product Overview: JMJD5 MS Standard C13 and N15-labeled recombinant protein (NP_001138820) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 50.7 kDa
• AA Sequence: MSREKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KDM8 lysine demethylase 8 [ Homo sapiens (human) ]
• Official Symbol: KDM8
• Synonyms: KDM8; lysine demethylase 8; JMJD5; bifunctional peptidase and arginyl-hydroxylase JMJD5; JmjC arginyl-hydroxylase; L-arginine (3R)-hydroxylase KDM8; arginyl C3-hydroxylase KDM8; jmjC domain-containing protein 5; jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; lysine (K)-specific demethylase 8; lysine-specific demethylase 8; EC 1.14.11.27
• Gene ID: 79831
• mRNA Refseq: NM_001145348
• Protein Refseq: NP_001138820
• MIM: 611917
• UniProt ID: Q8N371