Recombinant Human KCNK4 protein, Myc/DDK-tagged

• Cat.No.: KCNK4-30H
• Product Overview: Recombinant Human KCNK4 protein, fused to Myc/DDK-tag at C-terminus, was expressed in human 293 cells (HEK293).

Specification

• Description: This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Molecular Mass: 42.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method

Gene Information

• Gene Name: KCNK4
• Official Symbol: KCNK4
• Synonyms: KCNK4; potassium channel, subfamily K, member 4; potassium channel subfamily K member 4; K2p4.1; TRAAK; K2P4.1 potassium channel; two pore K+ channel KT4.1; two pore K(+) channel KT4.1; two pore potassium channel KT4.1; TWIK-related arachidonic acid-stimulated potassium channel protein; TRAAK1
• Gene ID: 50801
• mRNA Refseq: NM_033310
• Protein Refseq: NP_201567
• MIM: 605720
• UniProt ID: Q9NYG8