Recombinant Human KAT8 cell lysate

• Cat.No.: KAT8-1162HCL

Specification

• Description: The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: KAT8 K(lysine) acetyltransferase 8 [ Homo sapiens ]
• Official Symbol: KAT8
• Synonyms: KAT8; K(lysine) acetyltransferase 8; MYST histone acetyltransferase 1 , MYST1; histone acetyltransferase KAT8; FLJ14040; hMOF; MOF; MYST-1; lysine acetyltransferase 8; histone acetyltransferase MYST1; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; probable histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); MYST1
• Gene ID: 84148
• mRNA Refseq: NM_032188
• Protein Refseq: NP_115564
• MIM: 609912
• UniProt ID: Q9H7Z6
• Chromosome Location: 16p11.1
• Pathway: p53 pathway, organism-specific biosystem
• Function: acetyltransferase activity; histone acetyltransferase activity; contributes_to histone acetyltransferase activity (H4-K16 specific); contributes_to histone acetyltransferase activity (H4-K5 specific); contributes_to histone acetyltransferase activity (H4-K8 specific); metal ion binding; methylated histone residue binding; protein binding; transcription factor binding