Recombinant Human JPH2 Protein, MYC/DDK-tagged

• Cat.No.: JPH2-786H
• Product Overview: Recombinant human JPH2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 74 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: junctophilin 2[ Homo sapiens ]
• Official Symbol: JPH2
• Synonyms: CMH17; JP-2; JP2
• Gene ID: 57158
• mRNA Refseq: NM_020433.4
• Protein Refseq: NP_065166
• MIM: 605267
• UniProt ID: Q86VZ3