Recombinant Human ITPKA Protein, MYC/DDK-tagged

• Cat.No.: ITPKA-2641H
• Product Overview: Recombinant Human ITPKA protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 50.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ITPKA inositol-trisphosphate 3-kinase A [ Homo sapiens ]
• Official Symbol: ITPKA
• Synonyms: IP3-3KA; IP3KA
• Gene ID: 3706
• mRNA Refseq: NM_002220
• Protein Refseq: NP_002211
• MIM: 147521
• UniProt ID: P23677